肠道菌群在抑郁症、焦虑症及物质使用障碍中的作用

Research progress of gut microbiota in depression, anxiety and substance use disorders

目前大量研究证明神经-肠-脑轴在精神疾病中的重要作用,关注肠道菌群与精神疾病的相互关系和可能的调控机制。该文对几种关注较多的精神疾病,如抑郁症、焦虑症和物质使用障碍中肠道菌群的研究现状进行了总结,以期为肠道菌群成为治疗新靶点提供更多的临床证据。

At present,a large number of studies have proved the important role of the nerve-gut-brain axis in mental disorders,and focused on the correlation between gut microbiota and mental disorders and the potential regulating mechanisms.This paper summarizes the current research status of gut microflora in several mental disorders,such as depression,anxiety and substance use disorders,in order to provide more clinical evidence for gut microflora as a new target for treatment.