地佐辛复合丙泊酚麻醉在老年患者无痛胃镜术中的应用效果

Application effect of dizocine combined with propofol anesthesia in painless gastroscopy in elderly patients

目的分析地佐辛复合丙泊酚麻醉在老年患者无痛胃镜术中的应用效果。方法选取2016年6月~2019年6月我院收治的老年无痛胃镜术患者140例,回顾性分析患者的临床资料,按照手术麻醉方案分为对照组和观察组,各70例。两组均采用无痛胃镜术,对照组采用舒芬太尼复合丙泊酚麻醉,观察组采用地佐辛复合丙泊酚麻醉。比较两组给药后不同时期的平均动脉压、呼吸频率、脉搏氧饱和度等血气指标,丙泊酚总用量、患者苏醒时间以及不良反应发生率。结果麻醉前,两组平均动脉压、呼吸频率和脉搏氧饱和度比较,差异无统计学意义(P>0.05),麻醉后,观察组患者平均动脉压、呼吸频率和脉搏氧饱和度均远优于对照组,差异均有统计学意义(P<0.05);观察组患者丙泊酚总用量明显少于对照组,患者苏醒时间明显短于对照组,差异均有统计学意义(P<0.05);观察组不良反应发生率为4.29%(3/70),明显低于对照组的15.71%(11/70),差异有统计学意义(P<0.05)。结论在老年无痛胃镜术中,采用地佐辛复合丙泊酚麻醉,可显著优化麻醉期间老年患者的血气指标,缩短患者苏醒时间,且安全性较高,患者不良反应发生率明显降低,值得应用。

Objective To analyze the effect of dizocine combined with propofol anesthesia in painless gastroscopy in elderly patients.Methods A total of 140 elderly patients with painless gastroscopy admitted to our hospital from June 2016 to June 2019 were enrolled.The clinical data of the patients were retrospectively analyzed.According to the anesthesia program,the patients were divided into the control group and the observation group,with 70 cases in each group.The both groups were treated with painless gastroscopy.The control group was treated with Sufentanil combined with propofol anesthesia.The observation group was anesthetized with dizocine combined with propofol.The mean arterial pressure,respiratory rate,pulse oximetry and other blood gas indexes,total propofol dosage,patient recovery time and adverse reaction rate were compared between the two groups after administration.Results Before anesthesia,there were no significant differences in mean arterial pressure,respiratory rate and pulse oximetry between the two groups(P>0.05).After anesthesia,the mean arterial pressure,respiratory rate and pulse oximetry in the observation group were superior to the control group,and the difference was statistically significant(P<0.05).The total dose of propofol in the observation group was significantly lower than that in the control group.The recovery time of the observation group was significantly shorter than that of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 4.29%(3/70),which was significantly lower than that in the control group[15.71%(11/70)].The difference was statistically significant(P<0.05).Conclusion In elderly painless gastroscopy,the use of dizocine combined with propofol anesthesia can significantly optimize the blood gas index of elderly patients during anesthesia,shorten the recovery time of patients,with higher safety and less incidence of adverse reactions.It is worth applying.