沙库巴曲缬沙坦联合比索洛尔治疗慢性心力衰竭的临床效果观察

Clinical observation of the combination of sulbac and valsartan in the treatment of chronic heart failure

目的探讨沙库巴曲缬沙坦联合比索洛尔药物治疗慢性心力衰竭患者的临床效果。方法选择本院2016年10月至2018年4月收治的92例慢性心力衰竭患者作为研究对象,数字奇偶法分组后明确各组用药方式。对照组46例,选择比索洛尔展开治疗;观察组46例,选择沙库巴曲缬沙坦+比索洛尔展开治疗。对比两组患者用药效果。结果观察组患者用药显效率为63.04%、用药总有效率为97.83%,均高于对照组的30.43%、67.39%,差异有统计学意义(P<0.05);治疗前两组患者MLHFQ评分以及6 min步行距离比较差异无统计学意义,治疗后,观察组MLHFQ评分低于对照组,6 min步行距离多于对照组,差异均有统计学意义(P<0.05)。结论沙库巴曲缬沙坦联合比索洛尔药物治疗慢性心力衰竭患者效果显著,用药总有效率提高,MLHFQ评分降低,6 min步行距离增加,加快慢性心力衰竭患者的康复。

Objective To investigate the clinical effects of the choice of Shakuba valsartan combined with bisoprolol in patients with chronic heart failure. Methods 92 patients with chronic heart failure admitted to our hospital from October 2016 to April 2018 were selected as subjects. The digital parity method was used to determine the mode of administration of each group, 46 patients in the control group were treated with bisoprolol;46 patients in the observation group were treated with shakuba valsartan combined with bisoprolol. Compare the effect of medication between two groups. Results The effective rate of drug use in patients with chronic heart failure(63.04%) and the total effective rate of drug use(97.83%) were significantly higher in the observation group than in the control group(30.43%) and(67.39%). The difference was statistically significant(P<0.05).There was no significant difference between the two groups in the MLHFQ score and the 6-min walking distance before treatment. After treatment,the MLHFQ score of the observation group was lower than that of the control group, and the 6-min walking distance was more obvious than that of the control group, the difference was statistically significant(P<0.05). Conclusion The effective application of Shakuba valsartan combined with bisoprolol in patients with chronic heart failure during the drug treatment, the MLHFQ score decreased, the 6-min walking distance increased, the effect obviously, the recovery of patients with chronic heart failure is accelerated and effectively promoted.