摘要
Toll样受体(TLR)是一类在天然免疫系统中发挥重要作用的蛋白质,能够识别病原体分子。TLR可通过调节黏膜稳态、肠道菌群以及黏膜免疫等方面参与炎症性肠病(IBD)的发生。本文就TLR与IBD相关性的研究进展作一综述。
Toll-like receptors (TLR) are a group of proteins that play important roles in the innate immune system and can recognize pathogens. TLR may be involved in the development of inflammatory bowel disease (IBD) through the regulation of mucosal homeostasis, intestinal flora and mucosal immunity. This article reviewed the progress in research on correlation between TLR and IBD.
作者
燕彤
张军
YAN Tong;ZHANG Jun(the Third Clinical College, Nanjing Medical University, Nanjing (210000))
出处
《胃肠病学》
2019年第9期569-572,共4页
Chinese Journal of Gastroenterology
关键词
炎症性肠病
TOLL样受体
机制
治疗
Inflammatory Bowel Disease
Toll-Like Receptors
Mechanisms
Therapy
