曲马多超前镇痛用于甲状腺手术的效果观察

Preemptive Analgesia with Tramadol for Thyroid Surgery

目的观察在甲状腺手术中利用曲马多进行超前镇痛的镇痛效果。方法选择行择期甲状腺手术患者50例,随机分为超前镇痛组(A组)和常规镇痛组(B组),每组25例,两组患者均接受相同方式的全凭静脉麻醉(全麻诱导方式、术中维持方式均相同),术毕清醒常规拮抗拔管。观察15 min后送回病房,采用不同的镇痛方式。结果两者患者术后清醒拔管的时间无显著差异(P>0.05);VAS评分于T1、T2、T3、T4、T5时点A组明显低于B组,差异显著(P<0.05),于T6时点两组无显著差异(P>0.05);术后24 h内对止痛药的需求A组人数明显少于B组,差异显著(P<0.05)。结论在甲状腺择期手术中,手术开始前静注曲马多能有效减轻术后疼痛,具有超前镇痛的效果。

Objective To observe the analgesic effect of tramadol for preemptive analgesia in thyroid surgery. Methods Fifty patients undergoing elective thyroidectomy were randomly divided into preemptive analgesia group(group A) and routine analgesia group(group B). Each group had 25 patients. Both groups received the same general intravenous anesthesia(general anesthesia induction, intraoperative maintenance are the same), awake routine antagonistic extubation. After 15 minutes of observation, the patients were sent back to the ward with different analgesic methods. Results There was no significant difference in the time of conscious extubation between the two groups(P>0.05). The VAS score was significantly lower in group A than that in group B at T1, T2, T3, T4, T5(P<0.05), and there was no significant difference between the two groups at T6(P>0.05);The demand for analgesics in group A was significantly less than that in group B within 24 hours after operation(P<0.05). Conclusion In the selective thyroid surgery, intravenous tramadol injection before operation can effectively alleviate the pain after operation, and has the effect of preemptive analgesia.