谷赖胰岛素联合甘精胰岛素治疗老年2型糖尿病的临床疗效研究

Clinical Efficacy of Insulin Glutamic Combined with Insulin Glargine in the Treatment of Elderly Patients with Type 2 Diabetes Mellitus

目的分析探讨谷赖胰岛素联合甘精胰岛素治疗老年2型糖尿病的临床效果及应用价值。方法选取老年2型糖尿病患者40例,作为研究对象。按随机数表法分为对照组和研究组各20例,对照组采用赖脯胰岛素联合甘精胰岛素治疗,研究组采用谷赖胰岛素联合甘精胰岛素治疗。对比两组患者临床效果。结果两组患者治疗后相关指标均得到一定的控制效果,但是研究组患者治疗后的空腹血糖水平和餐后2 h血糖水平控制效果均好于对照组,日需胰岛素剂量也低于对照组,差异较大(P<0.05),具有统计学意义。结论谷赖胰岛素联合甘精胰岛素治疗老年2型糖尿病的临床疗效很好,对患者的血糖控制水平更佳,且日用胰岛素剂量较少,具有较高的临床实用价值,值得推广。

Objective To analyze the clinical effect and application value of insulin glulisine combined with insulin glargine in the treatment of type 2 diabetes mellitus in the elderly. Methods Forty elderly patients with type 2 diabetes mellitus were selected as the study subjects and divided into control group and study group with 20 cases each according to random number table method. The control group was treated with insulin lispro and insulin glargine. The study group was treated with insulin glulisine and insulin glargine. The clinical effects of the two groups were compared. Results The post-treatment related indexes of the two groups of patients were controlled to some extent, but the study group’s fasting blood glucose level and postprandial 2 h blood glucose level control effect were significantly better than the control group, and the daily insulin dose was also significantly lower than the control study. The difference was significant(P<0.05), which was statistically significant. Conclusion The efficacy of insulin glulisine combined with insulin glargine in the treatment of type 2 diabetes mellitus in the elderly is very good, and the blood glucose control level is better, and the daily insulin dose is less, with higher clinical practical value, it is worth promoting.