抗生素在呼吸内科临床治疗中的应用

Application of Antibiotics in Clinical Treatment of Respiratory Medicine

目的研究抗生素在呼吸内科临床治疗中的应用情况,以此分析抗生素应用种类、联用情况及合理性,以此为临床用药治疗提供指导。方法选择2017年1月至2018年6月我院呼吸内科收治的300例患者作为研究对象,调查分析300例患者的抗生素使用情况,对抗生素应用类型、占比和合理性等情况进行分析。结果 300例患者抗生素使用率达96.67%,应用率最高的抗生素为阿奇霉素、左氧氟沙星、头孢他啶;应用抗生素30种,其中单独应用抗生素例,占60.34%,二联用药例,占31.72%,三联用药例,占7.59%,四联用药例,占0.34%;其中抗生素属于治疗性用药占40.69%,预防性用药占52.41%,二者兼具占6.90%。结论呼吸内科应用抗生素治疗疾病用药比例较大,一定要严格控制抗生素使用,结合患者病情合理选择抗生素的种类,控制用药剂量,才能提高抗生素利用率,而且保证抗生素规范用药与合理用药。

Objective To study application of antibiotics in clinical treatment of respiratory medicine, analyze types, combination and rationality of antibiotics, provide guidance for clinical drug use. Methods Choose 300 patients admitted to respiratory medicine department of our hospital from January 2017 to June 2018 as research objects. Investigate and analyze antibiotic usage of 300 cases, analyze types, proportion and rationality of antibiotic. Results Antibiotic use rate of 300 cases was 96.67%, azithromycin, levofloxacin and ceftazidime ranked top three. Among them, antibiotics only cases accouted for 60.34%, dual therapy for 31.72%, triple therapy for 7.59% and quadruple therapy for 0.34%. Antibiotics for curative drugs accounted for 40.69% and preventive drugs for 52.41%, both for and 6.90%. Conclusion Antibiotics has bigger proportion in respiratory medicine department relatively in diseases treatment. It is necessary to control antibiotics usage strictly, select antibiotics types the according to patient’s condition, control the dosage of antibiotics, to improve utilization rate of antibiotics, ensure standard and rational usage of antibiotics.