成人手足口病合并化脓性扁桃体炎病例辨析并文献复习

Adult hand foot and mouth disease complicated with suppurative tonsillitis:a case report and literature review

手足口病(HFMD)是一种由肠道病毒(EV)感染引起的传染病,成人感染EV后引发的HFMD大多症状不明显或症状较轻微,可合并化脓性扁桃体炎,易误诊为病毒性疱疹或漏诊。深圳市罗湖区人民医院收治1例成人HFMD合并化脓性扁桃体炎患者,主要表现为发热、咽喉部疼痛,伴头痛、四肢肌肉及关节轻度疼痛,乏力,口腔和手足出现水疱伴触痛;查体示咽部充血;扁桃体肿大,可见白色分泌物;肠道病毒71型(EV71)RNA检测阳性。该患者发病前有手足口病患儿密切接触史。因成人也可感染EV导致HFMD及并发症,临床应早期诊断及隔离治疗,以避免病毒传播。

Hand foot and mouth disease(HFMD)is an infectious disease caused by enterovirus(EV)infection.Most HFMD in adults caused by EV has no obvious clinical manifestations or has very mild symptoms.The disease can be accompanied by suppurative tonsillitis and easily be misdiagnosed as viral herpes or missed diagosis.In Shenzhen Luohu People's Hospital,an adult patient with clinical features of HFMD complicated with suppurative tonsillitis was admitted for treatment and retrospectively analyzed in this report.The main manifestations of the patient were fever,sore throat accompanied by headache,slight pain in limb muscles and joints,fatigue,painful blisters on mouth,hands and feet with tender touch pain.The physical examinations showed pharyngeal congestion and tonsils large and swollen with white or yellow secretions on the surfaces.The detection of enterovirus 71(EV 71)RNA was positive.The patient had a close contact history with HFMD children prior to this illness'onset.Because EV can cause infection in adults leading to HFMD and complications,it is necessary to early diagnose,treat and isolate the patients to prevent the virus spread.