维生素D在儿童常见呼吸系统疾病中的研究进展

Study progress of vitamin D in respiratory diseases in children

维生素D是一种具有活性的脂溶性类固醇衍生物,能够促进肠道中的钙吸收并维持血清钙和磷酸盐浓度。近来研究发现缺乏维生素D除了影响骨骼发育,还可增加呼吸系统疾病、心血管疾病、自身免疫性疾病、神经精神类疾病、肿瘤和其他代谢类疾病的发生。研究提示,维生素D不足与儿童呼吸系统疾病的发生密切相关,现对维生素D的生理特性及与儿童常见呼吸系统疾病关系作一系统阐述。

Vitamin D is an active derivative of fat-soluble steroid,which can promotes the absorption of Ca in the intestine and maintains the concentrations of serum Ca in blood as well as phosphate.Recent researches found that the lack of vitamin D would increase the risk of respiratory diseases,cardiovascular diseases,autoimmune diseases,neuropsychiatric diseases,tumors and other metabolic diseases in addition to affecting the development of bones.More stu-dies have shown that low vitamin D levels is related to respiratory diseases in children.In this review,the physiological characteristics of vitamin D and the relationship with respiratory diseases in children were discussed.