唐山市城区女性肺癌发病的危险因素及预防对策

Risk factors and prevention measures of lung cancer in urban women in Tangshan city

目的:调查唐山市城区女性肺癌发病的主要危险因素,以降低女性肺癌在健康人群中的发病率。方法:选取2015年至2017年在唐山市人民医院(肿瘤医院)接受手术治疗的原发性肺癌女性患者250例,同时选择250例同期在我院参加体检的健康女性人群作为对照组,进行病例对照研究。利用统一调查表进行问卷调查后建立数据库,采用单因素和多因素Logistic回归进行分析。结果:单因素分析发现15个暴露因素与唐山市城区女性肺癌发病有关。多因素分析发现被动吸烟、住宅附近有大型污染工厂、职业接触粉尘、精神创伤、工作强度、曾服用口服避孕药为唐山市城区女性肺癌发生的危险因素,常吃蔬菜水果、经常饮茶、经常关注自身健康为保护因素。结论:被动吸烟、住宅附近有大型污染工厂、职业接触粉尘、精神创伤、工作强度、曾服用口服避孕药的城市女性更容易患肺癌。

Objective:To investigate the main risk factors of female lung cancer in urban area of Tangshan city,to reduce the incidence of female lung cancer.Methods:To select 250 female patients undergoing surgery for primary lung cancer in Tangshan People’s Hospital(Tumor Hospital) from 2015 to 2017,and select 250 healthy female who participated in physical examination in our hospital as control group for case-control study.After establishing a database using a unified questionnaire to conduct a questionnaire survey,univariate and multivariate Logistic regression were used for analysis.Results:Univariate analysis found that 15 exposure factors were associated with the incidence of female lung cancer in urban areas of Tangshan city,multi-factor analysis found passive smoking,large polluting factories near residential areas,occupational exposure to dust,trauma,work intensity,and oral contraceptive use in Tangshan City were risk factors for female lung cancer.Frequent eating fruits and vegetables,frequent tea drinking,and regular attention to their own health were the protective factors of female lung cancer in Tangshan city.Conclusion:Passive smoking,large polluting factories near residential areas,occupational exposure to dust,trauma,and work intensity,and urban women who have taken oral contraceptive pills are more likely to suffer from lung cancer.