早期动态18F-FDG PET/CT成像在实体肿瘤评估中的应用

Application of Early Dynamic 18F-FDG PET/CT Imaging in Solid Tumor Assessment

18F-FDG PET/CT常规代谢成像反应肿瘤的葡萄糖代谢及乏氧情况,而18F-FDG PET/CT早期动态成像能反映PET/CT成像早期肿瘤的灌注情况。由于肿瘤的异质性,在早期动态18F-FDG PET/CT成像,即18F-FDG PET/CT灌注成像中,存在独立于常规60 min18F-FDG PET/CT代谢成像的SUVmax(最大标准摄取值)高摄取区。因此,在临床工作中应用18F-FDG PET/CT早期动态成像,能够进一步对实体肿瘤的活性区域进行评估,能够更好评价患者预后、完善治疗方案。当前18F-FDG早期动态成像已经应用在肝癌、肾癌以及膀胱癌等实体肿瘤诊断中。早期动态18F-FDG PET/CT成像结合常规标准18F-FDG PET/CT代谢成像,对实体肿块进行一站式成像方法,能够更好的对肿瘤进行评估。

18F-FDG PET/CT Whole Body imaging reflects tumor glucose metabolism and hypoxia, while18F-FDG PET/CT early dynamic imaging can reflect PET/CT imaging of early tumors. Perfusion situation. Due to tumor heterogeneity, in early dynamic18F-FDG PET/CT imaging,18F-FDG PET/CT perfusion imaging, there is a SUVmax(maximum standard uptake value) independent of conventional 60 min18F-FDG PET/CT metabolic imaging. High intake area. Therefore, the application of 18F-FDG PET/CT early dynamic imaging in clinical work can further evaluate the active area of solid tumors, which can better evaluate the prognosis of patients and improve the treatment plan. The current 18F-FDG early dynamic imaging has been applied to the diagnosis of solid tumors such as liver cancer, kidney cancer and bladder cancer. Early dynamic18F-FDG PET/CT imaging combined with conventional standard18F-FDG PET/CT metabolic imaging, a one-stop imaging method for solid tumors, can better evaluate the tumor.