国际孕前队列研究现状

Transnational preconception cohort studies: a review

孕前队列研究是深入探究夫妇孕前暴露对亲代生殖健康和子代从儿童到成人期疾病影响的研究,其价值逐渐受到重视.本文对21项大样本国际前瞻性孕前队列研究现状进行简要综述,总结目前已有的国际孕前队列研究特点,为国内相关研究的开展提供借鉴.注重国际交流和跨学科合作、应用高效的数据系统或研究工具、以夫妇和子代为单位进行长期纵向调查将成为孕前队列研究的发展趋势.

Preconception cohort studies allow us to conduct in-depth investigations on exposures and heath related factors of couples before pregnancy,and to explore the impact on reproductive health of the couples and on short-and long-term health of the offspring.As a critical window into early life,this area has been gradually gaining much attention worldwide.This paper summarized the characteristics of 21 transnational preconception cohort studies with large samples size,to provide information for relevant researchers in China.Emphasis on international cooperation,application of highly efficient data systems or research tools,and long-term longitudinal survey on parents and their offspring are the direction of further preconception cohort researches.