摘要
人们对智力本质和它的进化史知之尚少.智力的"演化与选择"机制是一个非常重要的科学命题.本文从跨物种和跨尺度的角度研讨了6个重要的脑认知功能神经回路:(ⅰ)果蝇的基于价值的抉择;(ⅱ)学习记忆的去抑制机制;(ⅲ)视觉和嗅觉的跨模态学习与记忆;(ⅳ)电突触参与视觉学习;(ⅴ)模式分割的去相关性机制;(ⅵ)多稳态视觉感知机制.本文还从以上脑认知功能和脑结构在物种间的相似和演进出发,强调了开展跨物种和跨越不同空间尺度的脑科学研究的重要性和必要性.
Little is known about the nature of intelligence and its evolutionary history. The "evolution and selection" mechanism of intelligence is a very important issue for the scientific community to explore. This review will highlight six important cognitive study in Drosophila and discuss the common neural circuit mechanisms of the brain from a cross-species point of view. These are value-based decision making, disinhibition as a mechanism of learning and memory, cross-modal learning and memory of vision and olfaction,gap junction(electrical synapse) involvement in visual learning and memory, pattern segmentation, and multi-stable perception of vision. Together, these findings emphasize that the scientific community should advocate cross-species and cross-multiple-scale brain science.
作者
郭爱克
GUO AiKe(Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China;Institute of Neuroscience,Chinese Academy of Sciences,Shanghai 200031,China;University of Chinese Academy of Sciences,Beijing 100049,China;Shanghai Institute of Microsystem and Information Technology,Chinese Academy of Sciences,Shanghai 200050,China)
出处
《中国科学：生命科学》
CSCD
北大核心
2019年第10期1354-1374,共21页
Scientia Sinica(Vitae)
基金
中国科学院战略性先导科技专项(B类)(批准号:XDB02000000,XDB320100)
国家自然科学基金(批准号:31130430,30630262,9690013)
国家重点基础研究发展计划基础前沿项目(批准号:2006CB806600,G2000077800)
上海市市级科技重大专项(批准号:2018SHZDZX05)资助
关键词
果蝇
视觉飞行模拟器
学习和记忆
蘑菇体
伽马氨基丁酸能神经元
多巴胺
电突触
抉择
多模态整合
去抑制
模式分割
多稳态感知
类脑智能
演化+选择
物质变精神
自组织临界性
Drosophila
flight simulator
learning and memory
mushroom body
GABAergic neuron
dopamine
gap junction
decision making
multisensory integration
disinhibition
pattern segmentation
multi-stable perception
brain-inspired intelligence
evolution and selection
mind from matter
self-organized criticality
