四川省宜宾地区围产儿出生缺陷影响因素的病例对照研究

Case-control study on influencing factor of birth defects in Yibin city Sichuan Province

目的探讨四川省宜宾市围产儿出生缺陷影响因素,为制定出生缺陷防治策略提供参考依据。方法采用1:2匹配病例对照研究方法,探讨出生缺陷影响因素。结果有统计学意义的因素有:孕期接触噪音(OR=4.346)、家庭使用传统厨房燃料(OR=3.805)、孕期喜食生食(OR=3.386)、有缺陷儿生育史(OR=2.118)。结论生活环境、生活方式已经成为影响四川省宜宾市出生缺陷的重要因素,可将倡导适宜清洁的生活环境、良好健康的生活方式作为妇幼健康教育工作重点,以减少全市缺陷围产儿的发生。

Objective:To explore the influencing factor of birth defects in Yibin City Sichuan Province,and to provide the scientific evidence for comprehensive prevention of birth defects.Methods:1:2 matched case-control study was conducted to explore the influencing factor of top ten birth defects.Results:The following factor were found to be significantly related to birth defects:Noise exposure during pregnancy(OR=4.346),use traditional kitchen fuel(OR=3.805),preference for raw food during pregnancy(OR=3.386),and have birth history of defective children(OR=2.118).Conclusion:Environment and lifestyle have become important factors that affect birth defects in Yibin City,Sichuan Province.We can focus on the promotion of a clean living environment and a good and healthy lifestyle as the focus of maternal and child health education to reduce the occurrence of birth defects in the city.