摘要
Compared with surgery alone, post-operative adjuvant chemotherapy (ACT) for local colorectal cancer (CRC) can significantly improve survival.[1,2] The benefit of adjuvant fluorouracil (5-FU)-based chemotherapy in stage III CRC was established in the National Surgical Adjuvant Breast and Bowel Project (NSABP) Protocol C-01 trial[3] and consolidated in subsequent studies.
基金
grants from the National Natural Science Foundation of China(No.81872013)
the National Key Research and Development Program(No.2017YFC0108300)
the Science and Technology Planning Project of Guangdong Province(No.2017B020226005)
the National Clinical Key Specialty Construction Project(No.[2012]121).