糖尿病肾病患者肾功能检测指标的疗效

Effect of renal function test indexes in diabetic nephropathy patients

目的探讨肾功能检测指标在糖尿病肾病患者诊断及治疗中的影响。方法选取2018年1月-2019年1月茌平县人民医院收治的100例糖尿病肾病患者为观察组,选取同期100例健康体检者为对照组,均进行实验室检查,检测肾功能相关指标,观察肾功能相关指标检查结果。结果观察组患者的血清胱抑素C为(2.57±0.67)mg/L,血清β2-微球蛋白为(4.02±1.42)mg/L,尿素氮为(14.00±2.04)mmol/L、肌酐为(100.32±11.02)mg/L及尿微量白蛋为(443.36±12.32)mg/L,均高于对照组的(0.65±0.25)mg/L,(2.25±0.61)mg/L,(5.01±1.21)mmol/L,(60.37±9.08)mg/L及(10.01±2.51)mg/L,差异有统计学意义(P<0.05)。结论肾功能检测指标能有效的对糖尿病肾病患者进行疾病诊断及疾病状态判断,能监测肾脏病变程度。

Objective To investigate effect of renal function test indexes on the diagnosis and treatment of patients with diabetic nephropathy. Methods One hundred patients with diabetic nephropathy who were admitted to Chiping County People’s Hospital from January 2018 to January 2019 were selected as observation group,and one hundred patients with healthy physical examination in the same period were selected as control group. All of them were examined by laboratory to test the related indexes of renal function,and the results of renal function related examination indexes were observed. Results Serum cystatin C was(2.57 ±0.67)mg/L,serum β2-microglobulin was(4.02 ±1.42)mg/L,urea nitrogen was(14.00±2.04)mmol/L,creatinine was(100.32 ± 11.02)mg/L and urine microalbumin was(443.36±12.32)mg/L in observation group,which were higher than those in the control group(0.65±0.25)mg/L,(2.25±0.61)mg/L,(5.01±1.21)mmol/L,(60.37±9.08)mg/L and(10.01±2.51)mg/L,the differences were statistically significant(P<0.05). Conclusion The renal function test indexes could effectively diagnose and judge the disease status of diabetic nephropathy patients,and could monitor the degree of renal lesions.