紫外线治疗仪联合甘草酸苷治疗银屑病疗效观察

Observation on the therapeutic effect of ultraviolet therapy instrument combined with glycyrrhizin in the treatment of psoriasis

目的探讨窄谱中波紫外线治疗仪联合复方甘草酸苷治疗寻常银屑病的临床效果。方法选择2016年8月-2019年2月深圳市南山区蛇口人民医院收治的60例寻常银屑病患者为研究对象,按照不同治疗方法分为对照组和观察组各30例。对照组给予单纯窄谱中波紫外线治疗仪治疗,观察组联合给予复方甘草酸苷治疗,观察比较患者临床疗效和不良反应。结果观察组患者临床总有效率明显高于对照组,治疗后的PASI症状量表评分明显低于对照组,不良反应发生率明显低于对照组,差异均有统计学意义(P<0.05)。结论针对寻常银屑病患者给予窄谱中波紫外线联合复方甘草酸苷治疗,能明显缓解患者症状,降低患者不良反应,整体疗效更加明显,具有积极的临床推广价值。

Objective To investigate the clinical effect of narrow-band ultraviolet therapy instrument combined with compound glycyrrhizin in the treatment of psoriasis vulgaris. Methods A total of 60 patients with psoriasis admitted to Shekou People’s Hospital,Nanshan District,Shenzhen from August 2016 to February 2019 were selected as the study objects. According to different treatment methods,they were divided into control group and observation group with 30 cases in each. The control group was treated with narrow-band ultraviolet therapy instrument,while the observation group was treated with compound glycyrrhizin. The clinical efficacy and adverse reactions were observed and compared. Results The total clinical effective rate of the observation group was significantly higher than that of the control group. After treatment,the PASI symptom scale score of the observation group was significantly lower than that of the control group. The incidence of adverse reactions of the observation group was significantly lower than that in the control group. The differences were statistically significant(P <0.05). Conclusion Narrow-band ultraviolet radiation combined with compound glycyrrhizin for psoriasis vulgaris patients could significantly alleviate symptoms,reduce adverse reactions. The overall effect was more significant,and had a positive clinical promotion value.