我皮肤科门诊治疗急性与慢性荨麻疹的药物使用情况分析

Analysis of drug utilization for acute and chronic urticaria in our dermatology clinic

目的分析本皮肤科门诊治疗急性和慢性荨麻疹的药物应用情况。方法1200张急性荨麻疹处方与1200张慢性荨麻疹处方,对急性、慢性荨麻疹处方中不同类型药物应用情况进行回顾性分析。结果急性荨麻疹与慢性荨麻疹应用频次最高的药物均为抗组胺药,其次为抗过敏药,急性荨麻疹用药频次位于前3位的药物分别有抗组胺药、抗过敏药、激素类药物,慢性荨麻疹用药频次位于前3位的药物分别有抗组胺药、抗过敏药、外用药。抗组胺药物联合用药处方共有1250张,占52.1%;抗组胺药物二联用药处方共1183张,占49.29%;抗组胺药物三联用药处方共28张,占1.17%;抗组胺药物四联用药处方共39张,占1.63%。2400张处方中,不合理处方有792张,占33.0%,占比较高。结论临床治疗慢性荨麻疹与急性荨麻疹的首选药物为抗组胺药物,为了确保用药合理性,临床医师要对抗组胺药物联合用药指征、中成药、糖皮质激素类药物以及抗菌药物应用原则进行完全掌握。

Objective To analyze the drug utilization for acute and chronic urticaria in our dermatology clinic.Methods There were 1200 prescriptions of acute urticaria and 1200 prescriptions of chronic urticaria,and different types of drug utilization in prescriptions of acute and chronic urticaria was retrospectively analyzed.Results The most frequently drugs used for acute urticaria and chronic urticaria were antihistamines,followed by antiallergic drugs.The top three drugs for acute urticaria were antihistamines,antiallergic drugs and hormone drugs,while the top three drugs for chronic urticaria were antihistamines,antiallergic drugs and external drugs.There are 1250 prescriptions of antihistamines,accounting for 52.1%;1183 prescriptions of antihistamines,accounting for 49.29%;28 prescriptions of antihistamines,accounting for 1.17%;39 prescriptions of antihistamines,accounting for 1.63%.Of the 2400 prescriptions,792 prescriptions were unreasonable,accounting for 33.0%,which was relatively high.Conclusion Antihistamines are the first choice for the treatment of chronic urticaria and acute urticaria.In order to ensure the rationality of medication,clinicians should fully grasp the principles of combination indication of antihistamine drug,Chinese patent drug,glucocorticoids and antibacterials.