椎管内药物输注系统植入对难治性癌痛患者的镇痛效果及术后并发症分析

Analgesic effect and postoperative complications of drug delivery system implantation in patients with refractory cancer pain

目的:观察椎管内药物输注系统植入对难治性癌痛患者镇痛的疗效并分析其术后并发症。方法:选择本院2016年至2018年确诊收治的晚期恶性肿瘤伴难治性癌痛患者32例,行椎管内药物输注系统植入,对术前1天、术后第1天、3天、7天、14天、1个月、2个月、3个月疼痛、并发症及生活质量进行评估。结果:患者系统植入后癌痛情况明显改善(P<0.05);植入1周后生活质量明显提高,抑郁情况改善(P<0.05);植入后不良反应发生较少(P>0.05)。结论:椎管内药物输注系统植入是安全有效的镇痛治疗手段,值得在临床上推广应用。

Objective:To investigate the analgesic effect of intraspinal drug delivery system implantation in patients with refractory cancer pain and to analyze its complications.Methods:32 patients with advanced malignant tumors with refractory cancer pain diagnosed and treated in our hospital from 2016 to 2018 were selected.Intraspinal drug delivery system was implanted.Pain,complications and quality of life were assessed 1 day before operation,1 day,3 days,7 days,14 days,1 month,2 months,3 months after operation,and infection indexes were recorded and monitored.Results:The cancer pain was improved significantly after implantation(P<0.05).The quality of life and depression were improved significantly after 1 week of implantation(P<0.05).Less adverse reactions occurred after implantation(P>0.05).Conclusion:Intraspinal drug delivery system implantation is a safe and effective analgesic treatment,which is worthy of clinical application.