摘要
利益冲突是影响指南制订客观性、独立性和可靠性的重要因素,如何声明和管理利益冲突是指南制订者、使用者和研究者关注的焦点。本文分析比较了国内外指南制订的主要组织和机构对利益冲突的定义、分类及管理办法,在此基础上,就我国如何更好应对指南制订中的利益冲突提出思考与建议。
Conflicts of interest can affect the credibility,independence,and quality of clinical practice guidelines.Guideline developers,users,and researchers are trying to manage and reduce conflicts of interest worldwide.In this article,we analyzed and compared the definition,classification,and management strategies of conflicts of interest of the key national and international guideline developers,and give recommendations on how to address conflicts of interest in clinical practice guidelines in China.
作者
陈耀龙
王健健
詹思延
孙剑
靳英辉
李慧
商洪才
杨克虎
CHEN Yao-long;WANG Jian-jian;ZHAN Si-yan;SUN Jian;JIN Ying-hui;LI Hui;SHANG Hong-cai;YANG Ke-hu(Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,China;WHO Collaborating Center for Guideline Implementation and Knowledge Translation,Lanzhou 730000,China;Chinese GRADE Center,Lanzhou 730000,China;School of Public Health,Lanzhou University,Lanzhou 730000,China;Department of Epidemiology and Biostatistics,Peking University School of Public Health,Beijing 100191,China;Hepatology Unit,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Center for Evidence-Based and Translational Medicine,Zhongnan Hospital of Wuhan University,Wuhan 430072,China;Center for Evidence-Based and Translational Medicine,Wuhan University,Wuhan 430072,China;Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510120,China;Key Laboratory of Chinese Internal Medicine of Ministry of Education,Beijing Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)
出处
《协和医学杂志》
CSCD
2019年第6期685-691,共7页
Medical Journal of Peking Union Medical College Hospital
基金
国家重点研发计划(2018YFC1705500)
关键词
循证医学
临床实践指南
利益冲突
evidence-based medicine
clinical practice guideline
conflicts of interest
