超声评价睡眠不足与颈动脉粥样硬化的相关性

Correlation between Sleep deprivation and Carotid Atherosclerosis Based on Ultrasonography

目的探讨使用超声检测是否能提示睡眠不足与动脉粥样硬化之间的相关性。方法从我院体检的人群中随机抽取60例为研究对象,其中30例研究对象在持续3年的时间内平均每天睡眠时间不超过7 h,设为睡眠不足组;另外30例研究对象在持续3年的时间内平均每天睡眠时间在7 h以上,设为睡眠正常组。采用超声方式对所有研究对象颈总动脉内-中膜厚度、血流动力学参数以及超声-生理指标进行检测,比较两组研究对象的观察指标间是否具有差异。结果两组颈总动脉内-中膜厚度、血管阻力指数(RI)、血管壁运动度3项指标比较差异有统计学意义(P<0.05)。血管僵硬度和血管弹性扩张系数与匹兹堡睡眠质量量表评分具有线性相关关系(r=0.598,P<0.05;r=0.611,P<0.05)。结论长期睡眠不足的人群有颈动脉粥样硬化的危险,无临床表现时可以通过超声检测血管僵硬度与血管弹性扩张系数,并进行早期判断。

Objective To investigate the correlation between sleep deprivation and atherosclerosis based on ultrasonography.Methods A total of 60 patients who received physical examination in our hospital were set as the research objectives.Thirty patients,whose average daily sleep time was not more than 7 hours,were involved into the sleep deprivation group.Thirty patients,who could sleep for more than 7 hours daily,were involved into the sleep normal group.The carotid intima-media thickness(IMT),hemodynamic parameters,and ultrasound-physiological parameters were detected by ultrasonic method.The sleep quality was evaluated using the Pittsburgh Sleep Quality Scale(PSQI). Results There were significant differences in the carotid IMT,resitance index(RI),and degree of vessel wall motion between the two groups(P<0.05).The differences in vascular wall stiffness and distensibility coefficient were most obvious.There was a linear correlation between vascular wall stiffness and distensibility coefficient and the PSQI score(r=0.598,P<0.05;r=0.611,P<0.05).Conclusion Long-term sleep deprivation could bearisk factor for carotid atherosclerosis.When there is no clinical manifestation,it can be judged by ultrasound detection of vascular wall stiffness and distensibility coefficient.