不同剂量氨溴索治疗新生儿呼吸窘迫综合征临床疗效比较

Comparison of Clinical Effects of Different Doses of Ambroxol in the Treatment of Neonatal Respiratory Distress Syndrome

目的 探讨不同剂量氨溴索治疗新生儿呼吸窘迫综合征的意义。方法 随机将2018年1月~2019年1月收治的90例呼吸窘迫综合征新生儿分为两组,每组45例。观察组给予大剂量氨溴索治疗,对照组给予小剂量氨溴索治疗。比较两组临床疗效。结果 观察组总有效率、氧合指标等明显优于对照组(P <0. 05)。结论大剂量氨溴索治疗新生儿呼吸窘迫综合征效果显著,有利于改善临床症状以及生理指标。

Objective To investigate the significance of different doses of ambroxol in the treatment of neonatal respiratory distress syndrome.Methods 90 neonates with respiratory distress syndrome admitted to our hospital from January 2018 to January 2019 were randomly divided into two groups,45 in each group.The observation group was given a large dose of ambroxol and the control group was given a small dose of ambroxol.The clinical efficacy of the two groups was compared.Results The total effective rate,oxygenation index of the observation group were significantly better than the control group(P<0.05).Conclusions High-dose ambroxol is effective in the treatment of neonatal respiratory distress syndrome,which is beneficial to improve clinical symptoms and physiological indicators.