浮针疗法治疗膝骨性关节炎临床观察

Clinical Observation on Floating Needle Therapy in the Treatment of Knee Osteoarthritis

目的研究浮针疗法对膝骨性关节炎患者关节滑液中白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)水平的影响。方法选择2018年1月—2019年2月收治的76例膝骨性关节炎患者,根据随机双盲法分为2组,每组38例。对照组行电针治疗,观察组行浮针治疗。观察2组治疗后临床疗效、治疗前、1个疗程后关节滑液中IL-1β、IL-6及TNF-α炎症因子水平及中医证候积分。结果治疗后,观察组的总有效率(94.74%)低于对照组(78.95%),差异具有统计学意义(P<0.05);治疗1个疗程后,观察组关节滑液中的TNF-α、IL-1β及IL-6水平均较对照组低,差异具有统计学意义(P<0.05);治疗1个疗程后,观察组的中医证候积分低于对照组,差异具有统计学意义(P<0.05)。结论应用浮针疗法治疗膝骨性关节炎可明显降低患者关节滑液中IL-1β、IL-6及TNF-α水平,改善中医证候积分,提高疗效,值得应用推广。

Objective To study the effect of floating acupuncture on the levels of IL-1β,IL-6 and tumor necrosis factor-α(TNF-α)in synovial fluid of patients with knee osteoarthritis.Methods From January 2018 to February 2019,76 patients with knee osteoarthritis were randomly divided into two groups,with 38 patients in each group.The control group was treated with electro-acupuncture,and the observation group was treated with floating acupuncture.The clinical efficacy of IL-1β,IL-6 and TNF-αinflammation in synovial fluid of joints before and 1 course of treatment,factor level and TCM syndrome score were observed.Results After treatment,the total effective rate in the observation group(94.74%)was lower than that in the control group(78.95%),and the difference was statistically significant(P<0.05).After one course of treatment,the levels of TNF-α,IL-1βand IL-6 in synovial fluid of the observation group were significantly lower than those of the control group(P<0.05).After one course of treatment,the score of TCM syndromes in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Floating acupuncture therapy can significantly reduce TNF-α,IL-1βand IL-6 level,improve the score of TCM syndromes and the curative effect,which is worth popularizing.