刘氏手法联合玻璃酸钠治疗髌骨软化症的临床研究

Clinical Research of Liu’s Manipulation Combined with Sodium Hyaluronate in the Treatment of Chondromalacia Patellae

目的:观察刘氏手法联合玻璃酸钠治疗髌骨软化症的临床疗效,探讨其可能的作用机制。方法:选取髌骨软化症患者60例,随机分为玻璃酸钠组、手法组、手法联合玻璃酸钠组,每组20例,经治疗后观察各组患者视觉模拟评分及膝关节功能AKSS评分的动态变化。结果:3组患者治疗后5周、10周、15周VAS评分及AKSS评分均优于治疗前,差异均有统计学意义(P<0.01)。其中,手法联合玻璃酸钠组在治疗后各时间点VAS评分及AKSS评分均优于玻璃酸钠组和手法组,差异有统计学意义(P<0.01)。结论:刘氏手法联合玻璃酸钠治疗髌骨软化症能有效抑制炎性因子分泌,缓解关节疼痛,改善关节功能。

Objective:To observe the clinical effect of Liu’s manipulation combined with sodium hyaluronate in the treatment of chondromalacia patellae and explore the possible mechanism.Methods:60 patients with patellomalacia were randomly divided into sodium hyaluronate group,manipulation group and manipulation combined with sodium hyaluronate group,with 20 patients in each group.After treatment,the dynamic changes of visual simulation score,AKSS function score of knee joint in each group were observed.Results:VAS score and AKSS score at 5,10 and 15 weeks after treatment were better than before treatment in the three groups,and the differences were statistically significant(P< 0.01).Among them,VAS score,AKSS score in the sodium hyaluronate group and the sodium hyaluronate group were better than those in the sodium hyaluronate group and the sodium hyaluronate group at each time point after treatment(P< 0.01).Conclusion:Liu’s manipulation combined with sodium hyaluronate in the treatment of patellomalacia can effectively inhibit the secretion of inflammatory factors,relieve joint pain and improve joint function.