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GnRH类似物疫苗免疫去势效果的影响因素 被引量:1

Influencing Factors on Immune Castration Effect Using GnRH Analogue Vaccines
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摘要 利用GnRH类似物疫苗主动免疫动物机体可达到与手术去势类似的效果,同时避免了手术去势对动物机体产生的影响。抗原、佐剂、免疫次数、免疫剂量以及免疫时间都会对其免疫效果产生影响。采用GnRH类似物疫苗免疫动物通常需要有力的佐剂以及多次加强免疫来克服个体反应的差异性。 Active immunization with GnRH analogue vaccines can achieve similar effects with surgical castration in animals,avoiding the affects of surgical castration on animal health.Antigens,adjuvants,immunization times,immunization doses,and immunization time point of GnRH analogue vaccines all have effects on their immune response.Immunization with GnRH analogue vaccines in animals often requires potent adjuvants and multiple boosts to overcome differences in individual responses.
作者 邢雪静 尹国安 XING Xue-jing;YIN Guo-an(Heilongjiang Bayi Agricultural University,Daqing163319,China)
出处 《畜牧与饲料科学》 2019年第11期61-64,共4页 Animal Husbandry and Feed Science
基金 黑龙江省普通本科高等学校青年创新人才培养计划(UNPYSCT-2017107)
关键词 促性腺激素释放激素 免疫去势 并列二聚体 偶联蛋白 佐剂 疫苗 GnRH immune castration parallel dimer coupling protein adjuvant vaccine
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  • 1赵焕,章孝荣.GnRH免疫去势研究进展[J].动物医学进展,2004,25(6):16-18. 被引量:9
  • 2岳海宁.LHRH主动免疫对绵羊血清LH浓度的影响[J].中国兽医杂志,1996,22(6):12-13. 被引量:1
  • 3Peter J D. How far from a hormone-based contraceptive vaccine? Journal of Reproductive Immunology,2004,62 69 - 78.
  • 4Oonk H B, Turkstra J A . Testis size after immunocastration as parameter for the absence of boar taint. Livestock Production Science, 1995, 42: 63- 71.
  • 5Zeng X Y. Immunocastration of pigs in relation to breed, nutrition and sex:possible application in China. Utrecht University, the Netherlands, February, 2002d. ISBN 90-393-2946-X.
  • 6Jago J G, Cox N R, Bass J J, et al. Effect of prepubertal immunization against gonadotropin releasing hormone on the development of sexual and social behavior of bulls. Animal Science, 1997,75(10) :2609 - 2619.
  • 7Cui S, Chen Y F, Yue H N, et al. Sexual development and the effects of active immunization against GnRH in Chinese Tanyang ram lambs. Animal Reproduction Science, 2003, 77 : 129 - 139.
  • 8Godfrey S I, Walkden-Brown S W, Martin G B, et al. Immunisation of goat bucks against GnRH to prevent seasonal reproductive and agonistic behaviour. Animal Reproduction Science, 1996,44 : 41 - 54.
  • 9Meloen R H, Turkstra J A, Lankhof H, et al. Effcient immunocastration of male piglets by immunoneutralization of GnRH using a new GnRH-like peptide. Vaccine, 1994,12 (8) : 741- 746.
  • 10Adams T E, Daley C A, Adams B M, et al. Testis function and feedlot performance of bulls actively immunized against gonadotropin-releasing hormone: effect of implants containing progesterone and estradiol benzoate. Animal Science, 1993 ,71(4):811 - 817.

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