维持性血液透析患者发生透析中低血压的相关危险因素分析

A study on the related risk factors for intradialytic hypotension in maintenance hemodialysis patients

目的探讨维持性血液透析(MHD)患者透析中低血压(IDH)发生的相关危险因素,为临床防治提供参考依据。方法收集2016年6月至2018年6月147例MHD患者的临床资料,根据3个月内每次血液透析中IDH发生频率,分为无透析中低血压(no-IDH)组90例和透析中低血压(IDH)组57例,比较两组患者各项临床指标,并分析其与IDH发生的相关性。结果147例MHD患者中IDH的发病率为38.8%(57/147),多因素logistic回归分析结果表明,患者的年龄、超滤率、血白蛋白及低密度脂蛋白-胆固醇等指标与IDH的发生有关(均P<0.05)。结论年龄大、高超滤率、低血浆白蛋白水平、高低密度脂蛋白-胆固醇水平是MHD患者发生IDH的独立危险因素。

Objective o explore the relate risk factors for intradialytic hypotension(IDH)in maintenance hemodialysis(MHD)patients and provide clinical reference base for the prevention and treatment of IDH.Methods Collected the clinical datas of 147 maintenance hemodialysis patients from the Department of Nephrology and Blood Purification of Wenzhou Central Hospital during Jun.2016 to Jun.2018.These patients were divided into no intradialytic hypotension group(no-IDH)and intradialytic hypotension group(IDH)according to the intradialytic blood pressure in a 3-month period.Compared the differences in clinical indicators between the two groups and their association with IDH.Results The incidence rate of IDH was 38.8%in the147 patients.Multivariate Logistic regression analysis showed that age,ultrafiltration rate,plasma albumin and low density lipoprotein-cholesterol(LDL-C)were associated with IDH in MHD patients.Conclusion Elderly,higher ultrafiltration rate,low levels of plasma albumin and higher levels of LDL-C are independent risk factors for IDH in MHD patients.