肺表面活性物质在新生儿肺炎中的应用效果及对氧供、氧耗的影响观察

Application Effect of Pulmonary Surfactant in Newborns with Pneumonia and Influence for Oxygen Supply and Oxygen Consumption

目的:探究肺表面活性物质在新生儿肺炎中的应用效果及对氧供、氧耗的影响。方法:选取2015年1月-2018年11月本院收治的100例新生儿肺炎作为研究对象,根据治疗方式将其分为对照组(常规治疗)50例和观察组(常规治疗加肺表面活性物质)50例。比较两组治疗总有效率、治疗前后症状体征积分、氧供及氧耗指标。结果:观察组总有效率显著高于对照组,差异有统计学意义(P<0.05)。两组治疗前症状体征积分、氧供及氧耗指标比较,差异均无统计学意义(P>0.05);观察组治疗后症状体征积分、氧供及氧耗指标均显著优于对照组,差异均有统计学意义(P<0.05)。结论:肺表面活性物质在新生儿肺炎中的应用效果较好,且对患儿的氧供及氧耗状态有积极的改善作用,因此在本类新生儿中具有较高的应用价值。

Objective:To investigate the application effect of Pulmonary Surfactant in newborns with pneumonia and influence for oxygen supply and oxygen consumption.Method:A total of 100 newborns with pneumonia from January 2015 to November 2018 were chosen for the study,and they were divided into the control group(n=50,routine treatment)and the observation group(n=50,routine treatment and Pulmonary Surfactant)according to the differences of treatment methods.Then the total effective rates after the treatment,symptoms and signs integral,oxygen supply and oxygen consumption indexes before and after the treatment of two groups were compared.Result:The total effective rate of the observation group was significantly higher than that of control group,there was statistically significant difference(P<0.05).The symptoms and signs integral,oxygen supply and oxygen consumption indexes of two groups before the treatment were compared,there were no statistically significant differences(P>0.05).The symptoms and signs integral,oxygen supply and oxygen consumption indexes of the observation group after the treatment were significantly better than those of the control group,there were statistically significant differences(P<0.05).Conclusion:The application effect of Pulmonary Surfactant in newborns with pneumonia is better,and its improvement role for the oxygen supply and oxygen consumption of newborns are active,so its application value in these newborns is higher.