某院分化型甲状腺癌发病危险因素Logistic回归分析

Logistic Regression Analysis of Risk Factors of Differentiated Thyroid Carcinoma in a Hospital

目的:分析分化型甲状腺发病的危险因素,针对发病高危因素在日常生活、行为活动及医学预防上进行干预,以达到对其早诊断早治疗的目的。方法:回顾性分析2013年1月-2017年12月本院普外科行甲状腺手术治疗患者3133例的临床资料,分析分化型甲状腺癌患病情况及相关危险因素。结果:3133例甲状腺手术患者中,分化型甲状腺癌258例,占8.23%;Logistic回归分析显示,性别、年龄、甲状腺癌家族史、射线接触史及合并甲状腺结节与分化型甲状腺癌发病有关(P<0.05),且上述因素均为分化型甲状腺癌发病的独立危险因素(P<0.05)。结论:性别、年龄、射线接触史、甲状腺癌家族史及甲状腺结节是分化型甲状腺癌发病的危险因素,对于有射线接触史及甲状腺癌家族史的甲状腺结节女性患者,建议定期复查甲状腺彩超,必要时行甲状腺细针穿刺活检,以达到早诊断早治疗的目的。

Objective:To analyze the risk factors of differentiated thyroid carcinoma,and to intervene in daily life,behavioral activities and medical prevention aiming at the high risk factors,so as to achieve the goal of early diagnosis and treatment.Method:The clinical data of 3133 patients undergoing thyroid surgery from January 2013 to December 2017 in our hospital were retrospectively analyzed.The prevalence and risk factors of differentiated thyroid cancer carcinoma were analyzed.Result:Among 3133 patients undergoing thyroid surgery,258 cases(8.23%)were differentiated thyroid carcinoma.Logistic regression analysis showed that sex,age,family history of thyroid cancer,radiation exposure history and combined thyroid nodules were associated with the incidence of differentiated thyroid carcinoma(P<0.05),and the above factors were independent risk factors for the occurrence of differentiated thyroid carcinoma(P<0.05).Conclusion:Gender,age,radiation exposure history,family history of thyroid cancer and combined thyroid nodules are risk factors for thyroid cancer,for female patients with thyroid nodules who have a history of radiation exposure and family history of thyroid cancer,it is recommended to review thyroid color Doppler ultrasound regularly and perform fine needle biopsy if necessary in order to achieve the purpose of early diagnosis and treatment.