普鲁卡因与丁卡因在咽反射敏感患者口腔修复麻醉中的效果比较

Comparison of effects of Procaine and Tetracaine in oral anesthesia for patients with pharyngeal reflex sensitivity

目的:比较普鲁卡因、丁卡因在咽反射敏感患者口腔修复麻醉中的应用效果。方法:选取60例行口腔修复治疗的咽反射敏感患者作为研究对象,按随机数字表法将其分为对照组和观察组各30例,对照组实施普鲁卡因口咽部表面麻醉,观察组实施丁卡因口咽部表面麻醉,比较两组麻醉效果、咽肌紧张状况、治疗满意度、麻醉安全性。结果:观察组麻醉优良率为100.0%(30/30),明显高于对照组的80.0%(24/30),差异有统计学意义(P<0.05);操作中观察组咽肌紧张发生率为13.3%(4/30),明显低于对照组的36.7%(11/30),差异有统计学意义(P<0.05);观察组治疗感受和体会、修复体质量评分分别为(94.2±3.8)分与(95.7±2.3)分,均明显高于对照组的(89.3±5.4)分与(92.2±2.5)分,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:与普鲁卡因相比,丁卡因应用在咽反射敏感患者口腔修复治疗中的麻醉效果更显著,可明显减轻咽肌紧张,有效减少咽反射,提升患者满意度,且麻醉安全性良好。

Objective: To compare effects of Procaine and Tetracaine in oral anesthesia for patients with pharyngeal reflex sensitivity. Methods: Sixty patients with pharyngeal reflex sensitivity, who underwent oral prosthetic treatment, were selected as the subjects. They were divided into control group(n=30) and observation group(n=30) according to the random number table method. The control group was given Procaine oropharyngeal surface anesthesia, while the observation group used Tetracaine oropharyngeal surface anesthesia, The anesthetic effects, pharyngeal muscle tension, treatment satisfaction and anesthesia safety were compared between the two groups. Results: The excellent and good rate of anesthesia in the observation group was 100.0%(30/30), which was significantly higher than that in the control group(80.0%, 24/30), and the difference was statistically significant(P<0.05). The incidence of pharyngeal muscle tension in the observation group was 13.3%(4/30), which was significantly lower than that in the control group(36.7%, 11/30), and the difference was statistically significant(P<0.05). The treatment experience score and the prosthesis quality score of the observation group of(94.2±3.8) points, and(95.7±2.3) points were significantly higher than the control group of(89.3±5.4) points and(92.2±2.5) points, and the differences were statistically significant(P<0.05). However, there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusions: Compared with Procaine, Tetracaine in the oral prosthetic treatment of the patients with pharyngeal reflex sensitivity is more effective. It can significantly reduce the pharyngeal muscle tension, effectively reduce the pharyngeal reflex, and improve the patient satisfaction with good anesthesia safety.