某院质子泵抑制剂使用情况调查及干预措施

Investigation and intervention of proton pump inhibitors in our hospital

目的分析某院质子泵抑制剂(PPI)使用的合理性及干预措施,为促进临床合理使用PPI提供参考。方法通过医院信息系统随机抽取2018年1~4季度使用PPI的出院患者病历各30份,对PPI的使用情况进行合理性分析,制定相应的干预措施,并评价干预后的效果。结果调查及干预后,PPI用药指征、用法用量、联合用药、溶媒及配伍等方面的合理性均有明显提高,但仍存在部分无指征预防用药情况。结论某院开展的以临床药师为主要参与人员的PPI使用情况调查和干预效果显著,但仍需继续加强PPI使用情况的监测与干预。

Objective To analyze the rationality of the use of proton pump inhibitors(PPI) in our hospital and the intervention measures, so as to provide reference for promoting the rational use of PPI in clinic. Methods 30 medical records of discharged patients using PPI were randomly selected from the hospital information system in the first four quarters of 2018. The rationality of the use of PPI was analyzed, the corresponding intervention measures were formulated, and the effect of the intervention was evaluated. Results After investigation and intervention, the rationality of PPI indications, usage and dosage, combination of drugs, solvent and compatibility were significantly improved, but there were still some cases of non-indication preventive drug use. Conclusion The results of PPI use survey and intervention carried out in our hospital with clinical pharmacists as the main participants are remarkable, but the monitoring and intervention of PPI use need to be strengthened.