高龄2型糖尿病患者甲状腺结节患病情况分析

Analysis of Thyroid Nodule in Elderly Patients with Type 2 Diabetes

目的:分析高龄2型糖尿病患者的甲状腺结节患病情况。方法:纳入本院2017年1月-2018年11月收治的高龄2型糖尿病患者100例作为观察组,纳入同期健康体检的100例高龄非糖尿病受检者作为对照组。收集两组研究对象的一般资料,检测空腹血糖、甲状腺激素水平,进行甲状腺彩超检查,对比两组的甲状腺结节特点,并分析观察组患者的空腹胰岛素水平与有无甲状腺结节的相关性。结果:观察组的甘油三酯、空腹血糖、谷丙转氨酶水平均高于对照组,HDL-C水平低于对照组,差异均有统计学意义(P<0.05)。观察组的甲状腺结节检出率显著高于对照组,差异有统计学意义(P<0.05);经甲状腺超声检查结果显示,观察组与对照组均多见多发结节,观察组的甲状腺结节直径1~2 cm的例数多于对照组,差异有统计学意义(P<0.05)。观察组发生甲状腺功能异常17例,多于对照组的6例,差异有统计学意义(χ2=5.945,P<0.05)。结论:高龄2型糖尿病患者的甲状腺结节疾病较常发生,对于高龄2型糖尿病患者应当重视甲状腺疾病的筛查工作,以便于早期发现甲状腺结节并及早干预与治疗,以此提高老年患者的生活质量。

Objective: To analyze the thyroid nodule in elderly patients with type 2 diabetes. Method: A total of 100 elderly patients with type 2 diabetes admitted to our hospital from January 2017 to November 2018 were included as the observation group, and 100 elderly non-diabetic subjects who were included in the health examination during the same period were included as the control group. The general information of the two groups of subjects was collected, fasting blood glucose and thyroid hormone levels were detected, thyroid color ultrasound was performed, and the characteristics of thyroid nodules in the two groups were compared, the correlation between fasting insulin level and thyroid nodule was analyzed. Result: The triglycerides(TG), fasting blood glucose(FBG), alanine aminotransferase(ALT) in the observation group were significantly higher than those in the control group, the high density lipoprotein(HDL-C) in the observation group was significantly lower than that in the control group, the differences were statistically significant(P<0.05). The detection rate of thyroid nodules in the observation group was significantly higher than that in the control group, the difference was statistically significant(P<0.05). The results of transthyroid ultrasound showed that multiple nodules were more common in both the observation group and the control group, and the number of thyroid nodules with a diameter of 1-2 cm in the observation group was more than that in the control group, with statistically significant difference(P<0.05). There were 17 cases of abnormal thyroid function in the observation group, more than 6 cases in the control group, the difference was statistically significant( χ2=5.945, P<0.05). Conclusion: Thyroid nodule disease is more common in elderly type 2 diabetes patients, for elderly type 2 diabetes patients, thyroid disease screening should be emphasized so as to facilitate early detection of thyroid nodule and early intervention and treatment, so as to improve the quality of life of elderly patients.