隔姜灸配合中药离子导入对原发性痛经患者的影响

Effect of ginger moxibustion combined with Chinese medicine iontophoresis on patients with primary dysmenorrhea

目的:观察隔姜灸配合中药离子导入对原发性痛经患者症状改善、血清血小板活化因子(PAF)水平及子宫动脉搏动指数的影响。方法:选择在本院接受相关治疗的114例原发性痛经患者,依据自愿接受治疗方案的不同将其分为两组,对照组57例接受布洛芬胶囊治疗,研究组57例接受隔姜灸配合中药离子导入治疗。在为期3个月经周期的治疗结束后进行疗效评价,统计症状改善情况,比较PAF、血小板活化因子乙酰水解酶(PAF-AH)、血小板黏附率,测定子宫动脉血流动力学,检测血清超敏C-反应蛋白(hs-CRP)与白介素-6(IL-6)水平。结果:研究组总有效率明显高于对照组;治疗后两组不同症状积分水平与治疗前相比均明显下降,且研究组治疗后不同症状积分水平均明显低于对照组;治疗后两组PAF、血小板黏附率与治疗前相比均明显下降,PAF-AH与治疗前相比均明显上升,且研究组治疗后PAF、血小板黏附率均明显低于对照组,PAF-AH明显高于对照组;治疗后研究组搏动指数、阻力指数、收缩舒张峰值比与治疗前相比均明显下降,且研究组治疗后搏动指数、阻力指数、收缩舒张峰值比均明显低于对照组;治疗后两组血清hs-CRP与IL-6水平测定结果与治疗前相比均明显下降,且研究组治疗后血清hs-CRP与IL-6水平测定结果均明显低于对照组。结论:隔姜灸配合中药离子导入有助于确切提高原发性痛经治疗总有效率,降低不同症状积分水平,合理改善PAF、PAF-AH、血小板黏附率,搏动指数、阻力指数、收缩舒张峰值比下降明显,血清hs-CRP与IL-6水平趋于正常。

Objective:To observe the effects of Ginger moxibustion combined with iontophoresis of traditional Chinese medicine on the improvement of symptoms,serum platelet activating factor(PAF)level and uterine artery pulsation index in patients with primary dysmenorrhea.Methods:A total of 114 patients with primary dysmenorrhea who were treated in our hospital from August 2017 to February 2019 were divided into two groups according to the different treatment schemes.57 patients in the control group were treated with ibuprofen capsules,and 57 patients in the study group were treated with Ginger moxibustion combined with iontophoresis of traditional Chinese medicine.After three menstrual cycles of treatment,the curative effect was evaluated and the improvement of symptoms was counted.PAF,PAF-AH and platelet adhesion rate were compared,uterine artery hemodynamics was measured,and levels of serum hs-CRP and IL-6 were measured.Results:The total effective rate of the study group was significantly higher than that of the control group.After treatment,the scores of different symptoms in the two groups were significantly lower than those before treatment,and the scores of different symptoms in the study group were significantly lower than those in the control group.After treatment,PAF and platelet adhesion rate in the two groups were significantly lower than those before treatment,PAF-AH was significantly higher than that before treatment,and PAF and platelet adhesion rate in the study group were significantly lower than those in the control group,PAF-AH was significantly higher than that in the control group.After treatment,the pulsation index,resistance index and peak systolic-diastolic ratio in the study group were significantly lower than those before treatment,and the pulsation index,resistance index and peak systolic-diastolic ratio in the study group were significantly lower than those in the control group.After treatment,the levels of serum hs-CRP and IL-6 in the two groups were significantly lower than those before treatment,and the levels of serum hs-CRP and IL-6 in the study group were significantly lower than those in the control group.Conclusions:Ginger moxibustion combined with iontophoresis of traditional Chinese medicine is helpful to improve the total effective rate of primary dysmenorrhea treatment,reduce the score levels of different symptoms,rationally improve PAF,PAF-AH,platelet adhesion rate,and the pulse index,resistance index,peak systolic-diastolic ratio are decreased significantly,and serum hs-CRP and IL-6 levels tend to be normal.