乳腺癌保乳术后三维适形放疗与调强放疗的疗效及不良反应

The Efficacy and Adverse Reactions of Three-dimensional Conformal Radiotherapy and Intensity-modulated Radiotherapy after Breast-conserving Breast Conserving Surgery

目的分析乳腺癌保乳术后三维适形放疗与调强放疗的疗效及不良反应。方法选取我院收治的行保乳术的乳腺癌患者81例,采取数字随机法分成2组,对照组(n=40)应用三维适形放疗,观察组(n=41)则应用调强放疗,比较2组临床疗效及不良反应。结果观察组优良率97.50%,对照组优良率82.50%,观察组患者保乳术美容效果优于对照组,差异有统计学意义(P<0.05)。观察组皮肤不良反应率12.20%,对照组皮肤不良反应率30.00%,观察组患者皮肤不良反应率低于对照组,差异有统计学意义(P<0.05)。结论乳腺癌保乳术后调强放疗疗效较常规三维适形放疗更好,不良反应发生率更低,是一种优秀放疗方法。

Objective To analyze the efficacy and adverse reactions of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy after breast-conserving breast-conserving surgery.Methods Eighty-one patients with breast cancer who underwent breast-conserving surgery were enrolled in our hospital.The patients were divided into two groups by digital randomization method.The control group(n=40)was treated with three-dimensional conformal radiotherapy,and the observation group(n=41)was treated with intensity-modulated radiotherapy.The clinical efficacy and adverse reactions of the two groups were compared.Results The excellent and good rate of the observation group was 97.50%,and the excellent rate of the control group was 82.50%.The cosmetic effect of breast-conserving surgery in the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The adverse reaction rate of skin in the observation group was 12.20%,and the adverse reaction rate of skin in the control group was 30.00%.The adverse reaction rate of the skin in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The efficacy of intensity-modulated radiotherapy after breast-conserving surgery is better than conventional threedimensional conformal radiotherapy,and the incidence of adverse reactions is lower.It is an excellent radiotherapy method.