高通量聚砜膜血液透析对左卡尼汀干预下ESRD患者血清免疫因子的影响

Effect of High-flux Polysulfone Membrane Hemodialysis on Serum Immune Factors in Patients with ESRD Treated with L-carnitine

目的探讨高通量聚砜膜血液透析对左卡尼汀干预下终末期肾病患者血清免疫因子的影响。方法选取2017年1月~12月间我科收治42例接受高通量血液透析治疗ESRD患者为试验对象,经完全随机及左卡尼汀联合干预,分为联合组(n=22)和对照组(n=20)。比较两组患者血清常见免疫因子变化。结果联合组经治疗后血清免疫因子均与对照组存在显著性差异(P<0.05)。结论终末期肾病患者在接受血液透析治疗同时联合左卡尼汀有效提高机体免疫力,减轻炎症及改善症状,为临床新途径探讨提供依据。

Objective To investigate the effect of HFHD on serum immune factors in patients with ESRD treated by L-carnitine.Methods 42 cases of ESRD patients received high throughput hemodialysis in our department of-12 in January 2017 were selected and treated with complete random and levocarnitine intervention and divided into combined group(n=22)and control group(n=20).The changes of serum immune factors were compared between the two groups.Results There was a significant difference in serum immune factors between the combined group and the control group after treatment(P<0.05).Conclusion The patients with ESRD combined with HFHD more effectively improve the immune ability of the body,which can help to alleviate the disease and improve the symptoms,and provide the basis for the discussion of the new clinical pathway.