内镜下用药止血治疗消化性溃疡出血的应用效果

Application effect of endoscopic hemostasis in the treatment of peptic ulcer bleeding

目的探讨内镜下用药止血治疗消化性溃疡出血的应用效果。方法选取2017年2月~2019年2月我院收治的84例消化性溃疡出血患者作为研究对象,按照随机数字表法将其分为内镜组(42例)与药物组(42例)。内镜组采用内镜下白眉蛇毒血凝血酶注射止血,药物组采用奥美拉唑注射治疗。比较两组患者的止血效果、止血时间、输血量及住院时间、术后1周再出血率、外科手术治疗率以及并发症的发生情况。结果内镜组的即时止血率、止血成功率高于药物组,术后1周再出血率低于药物组,止血时间、住院时间短于药物组,输血量少于对照组,差异有统计学意义(P<0.05)。内镜组治疗期间未见穿孔、吸入性肺炎等并发症,药物组未见恶心、呕吐等并发症。两组的外科手术治疗率比较,差异无统计学意义(χ2=0.263,P=0.608)。结论内镜下治疗消化性溃疡出血效果良好,内镜下用药止血效果良好,临床可根据患者实际情况,选择个体化治疗方案。

Objective To evaluate the clinical effect of endoscopic treatment for peptic ulcer bleeding.Methods Eighty-six patients with peptic ulcer bleeding who were admitted to our hospital from February 2017 to February 2019 were enrolled in the study as subjects.According to the random number table method,they were divided into the endoscopic group(42 cases)and the drug group(42 cases).The endoscopic group was treated with endoscopic White Bloodsucking Venom Blood Thrombin Injection to stop bleeding,and the drug group was treated with Omeprazole.The hemostatic effect,hemostatic time,blood transfusion volume and hospitalization time,rebleeding rate 1 week after surgery,surgical treatment rate and complications were compared between the two groups.Results The immediate hemostasis rate and hemostasis success rate of the endoscopy group were higher than that of the drug group,the rebleeding rate was lower than that of the drug group 1 week after operation,the hemostasis time and hospitalization time were shorter than the drug group,and the blood transfusion volume was lower than that of the control group,the differences were statistically significant(P<0.05).No complications such as perforation and aspiration pneumonia were observed during the endoscopic treatment,no complications such as nausea and vomiting were observed in the drug group.The surgical treatment rate of the observation group was 2.38%,while that of the control group was 7.14%,there was no significant difference between the two groups(χ2=0.263,P=0.608).Conclusion Endoscopic treatment of peptic ulcer bleeding is good,endoscopic medication has a good hemostasis effect,clinically,according to the actual situation of patients,choose individualized treatment.