硫酸镁与硝苯地平联合应用于妊娠期高血压疾病患者中的效果研究

Study on the Effect of Magnesium Sulfate Combined with Nifedipine in Patients with Hypertension during Pregnancy

目的分析和研究妊娠期高血压疾病患者中采用硫酸镁联合硝苯地平治疗的应用效果。方法随机选取2018年3月-2019年3月在我院住院的妊娠期高血压疾病患者60例作为研究对象,随机分成对照组(30例)和观察组(30例)。对照组采用硝酸镁单独治疗,观察组采用硫酸镁与硝苯地平联合治疗,比较两组患者的应用疗效和不良反应情况。结果观察组和对照组的治疗总有效率分别为96.78%、74.19%,差异具有统计学意义(P<0.05),两组患者不良反应发生率分别为6.45%、22.58%,观察组患者的不良反应发生率明显低于对照组(P<0.05)。结论对妊娠期高血压疾病患者采用硫酸镁与硝苯地平联合治疗的效果明显,且不良反应发生率较小,值得在临床中推广应用。

Objective To analyze and study the therapeutic effect of magnesium sulfate combined with nifedipine in patients with hypertension during pregnancy. Methods 60 cases of patients with gestational hypertension who were hospitalized in our hospital from March 2018 to March 2019 were randomly selected as research objects, and 30 cases were randomly divided into the control group and the observation group. The control group was treated with magnesium nitrate alone, while the observation group was treated with magnesium sulfate combined with nifedipine. The efficacy and adverse reactions of the two groups were compared. Results The total effective rate of observation group and control group was 96.78% and 74.19%, respectively, the difference was statistically significant(P<0.05). The incidence of adverse reactions in the two groups was 6.45% and 22.58%, respectively, and the incidence of adverse reactions in the observation group was significantly lower than that in the control group(P<0.05). Conclusion Magnesium sulfate combined with nifedipine is effective in treating hypertensive disease during pregnancy, and the incidence of adverse reactions is little.