超微血管成像技术检测颈动脉斑块新生血管价值探讨

Value of superb micro-vascular imaging in detecting neovascularization of carotid plaque

目的:探讨超微血管成像技术(SMI)在检测颈动脉斑块新生血管中的优缺点。方法:选取进行常规彩色多普勒颈动脉超声检查中发现的62例颈动脉粥样硬化病人,进行常规彩色多普勒超声检查后继续SMI筛查,查出有新生血管信号的颈动脉斑块70个,进一步进行超声造影(CEUS)检查,比较两种方法检测颈动脉斑块中新生血管数量的一致性。结果:将SMI检测出新生血管的斑块根据新生血管的数量、形态分布情况进行分级,经颈动脉SMI检查后评分为0级的斑块10例,1级的斑块35例,2级的斑块25例。经颈动脉CEUS检查,评分为0级的斑块15例,1级的斑块35例,2级的斑块20例。两种模式检测颈动脉斑块内新生血管的一致性很好(Kappa=0.769,P<0.05)。结论:SMI与CEUS检测颈动脉斑块内新生血管有很好的一致性,且SMI的安全性高,操作简便,可重复性强,在评价颈动脉斑块新生血管中有重要的参考价值,可作为检测颈动脉斑块新生血管的重要方法。

Objective:To investigate the clinical significnace of superb micro-vascular imaging(SMI) in the detection of neovascularization of carotid plaque.Methods:Sixty-two patients with carotid atherosclerosis were identified using the routine color Doppler,and 70 carotid plaque cases with new blood vessel signal were screened using SMI,and further examined using contrast-enhanced ultrasound(CEUS).The consistency of two methods in detecting the number of neovascularization in carotid plaque was compared.Results:The plaques were graded according to the distribution and number of neovascularization detected by SMI,grade 0 in 10 cases,grade 1 in 35 cases and grade 2 in 25 cases were identified according to the score of SMI.The grade 0 in 15 cases,grade 1 in 35 cases and grade 2 in 20 cases were identified according to the score of carotid CEUS.The consistency of SMI CEUS in detecting the neovascularization of carotid plaque was good(Kappa=0.769,P<0.05).Conclusions:SMI has good coincidence with CEUS in the diagnosis of neovascularization of carotid plaque.SMI has high safety,easy operation and high reproducibility.SMI has important reference value in evaluating the neovascularization of carotid plaque,and can be used as an important method in the diagnosis of neovascularization of carotid plaque.