站立斜床联合高压氧对卒中后气管切开患者肺部感染的临床疗效

Clinical effect of standing inclined bed combined with hyperbaric oxygen on pulmonary infection in patients with tracheotomy after stroke

目的观察站立斜床联合高压氧对卒中后气管切开患者肺部感染的临床疗效。方法将广东省第二中医院60例卒中后气管切开伴发肺部感染的患者按随机数字表法分成常规治疗组和联合组,每组30例。常规治疗组采用常规治疗,联合组在常规治疗基础上给予站立斜床联合高压氧治疗。比较两组患者治疗前、治疗后3、7 d的静脉血中白细胞(WBC)、中性粒细胞计数(NE#)、C反应蛋白(CRP)水平,并比较两组临床疗效。结果治疗后3、7 d,联合组患者的WBC、NE#、CRP水平均低于治疗前,差异具有统计学意义(P<0.05);治疗后3 d,联合组患者的WBC、NE#、CRP水平均低于常规治疗组,差异具有统计学意义(P<0.05);治疗后7 d,联合组患者的WBC水平低于常规治疗组(P<0.05)。治疗后,联合组患者的治疗总有效率为93.33%,显著高于常规治疗组的73.33%(P<0.05)。结论与常规治疗相比,站立斜床联合高压氧治疗卒中后气管切开患者肺部感染的效果更理想,可改善炎症,更有助于患者肺功能的恢复。

Objective To observe the clinical effect of standing inclined bed combined with hyperbaric oxygen on pulmonary infection in patients with tracheotomy after stroke. Methods Sixty patients with tracheotomy and pulmonary infection after stroke in the Guangdong second traditional Chinese medicine hospital were selected and divided into conventional treatment group and combined group according to the random number table method, with 30 cases in each group. The conventional treatment group was treated with conventional treatment, while the combined group was treated with standing inclined bed and hyperbaric oxygen on the basis of conventional treatment. The levels of white blood cells(WBC), neutrophils(NE#) and C-reactive protein(CRP) in the venous blood of the two groups before treatment and at 3, 7 days after treatment were compared, and the clinical effects of the two groups were compared. Results At 3, 7 days after treatment, levels of WBC, NE# and CRP in the combined group were lower than those before treatment, and the differences were statistically significant(P<0.05). The levels of WBC, NE# and CRP in the combined group were lower than those in the conventional group at 3 days after treatment, and the differences were statistically significant(P<0.05). At 7 days after treatment, the WBC level in the combined group was lower than that in the conventional group(P<0.05). After treatment,the total effective rate of treatment in the combined group was 93.33%, which was significantly higher than 73.33% in the conventional group(P<0.05). Conclusion Compared with the routine treatment, the standing inclined bed combined with hyperbaric oxygen in the treatment of pulmonary infection in patients with tracheotomy after stroke has more ideal effect,which can improve inflammation and help the recovery of pulmonary function in patients.