氧氟沙星联合地塞米松治疗化脓性中耳炎的临床效果

Clinical effect of ofloxacin combined with dexamethasone in the treatment of suppurative otitis media

目的观察氧氟沙星联合地塞米松治疗化脓性中耳炎的临床效果。方法回顾性分析本院收治的136例化脓性中耳炎患者的临床资料,根据治疗方式的不同将其分为对照组和试验组,每组68例。对照组给予氧氟沙星滴耳液治疗,试验组在此基础上联合地塞米松治疗。比较两组的临床疗效。结果试验组的治疗总有效率明显高于对照组,差异具有统计学意义(P<0.05)。试验组的不同频率听阈水平均明显高于对照组,差异具有统计学意义(P<0.05)。试验组的病原菌清除率明显高于对照组,差异具有统计学意义(P<0.05)。结论氧氟沙星联合地塞米松治疗化脓性中耳炎的效果显著,不仅能改善患者临床症状及体征,提高病原菌清除率,而且能促进听力恢复正常,值得临床推广应用。

Objective To observe the clinical effect of ofloxacin combined with dexamethasone in the treatment of suppurative otitis media. Methods The clinical data of 136 cases of suppurative otitis media patients admitted in our hospital were retrospectively analyzed. According to the different treatment methods, the patients were divided into control group and experimental group, with 68 cases in each group. The control group was treated with ofloxacin ear drops and the experimental group was treated with dexamethasone on this basis. The clinical efficacy of the two groups were compared.Results The total effective rate of treatment in the experimental group was significantly higher than that in the control group, the difference was statistically significant(P <0.05). The hearing threshold levels of different frequencies in the experimental group were significantly higher than those in the control group, the differences were statistically significant(P<0.05). The clearance rate of pathogens in the experimental group was significantly higher than that in the control group,the difference was statistically significant(P<0.05). Conclusion Ofloxacin combined with dexamethasone in the treatment of suppurative otitis media has a significant effect. It can not only ameliorate the clinical symptoms and signs of patients,improve the clearance rate of pathogens, but also promote the recovery of hearing, which is worthy of clinical application.