手性低聚物/聚合物诱导非手性物质手性组装的研究进展

Advances in Chiral Assembly of Achiral Substance Induced by Chiral Oligomer/Polymer

手性低聚物/聚合物充当支架(模板)诱导非手性物质的手性组装是近年来的研究热点之一。该方法不仅克服了传统手性聚合物合成方法中使用价格昂贵的手性试剂以及复杂的合成路线等缺点,还丰富了手性物质的种类,在生命科学特别在研究手性的起源上具有较为重要的科学意义。本文主要从天然和人工合成的手性低聚物/聚合物两类支架(模板)诱导非手性物质手性组装的发展、手性支架(模板)诱导非手性聚合物和无机物手性组装的研究进展以及该方法未来的研究重点和发展趋势这几个方面展开综述。

The chiral oligomers/polymers are usually used as the scaffolds or templates to induce the helicity/chirality of achiral substances,which has been one of the research hotspots in recent years.Compared to traditional methods,this method can not only avoid the use of expensive chiral reagents and complex synthetic routes,but also enrich the types of chiral substances,which has potential applications in bioscience,especially in the field of exploring the origin of chirality.In this review,we briefly introduce the historical development of chiral assembly of achiral substances induced by natural/synthetic chiral oligomers/polymers.Additionally,the advances in chiral assembly of achiral polymers and inorganic compounds induced by chiral oligomers/polymers scaffolds(templates)strategies are also discussed.The research focuses and development trends of this method are summarized in the end.With implications for biological helices and functions,further applications of chiralityresponsive polymers based novel chiral materials as enantioselective catalysts and adsorbents will be an interesting and important challenge.In the future,oligomer/polymer scaffolds(templates)strategies will receive much more attention from scientists in the fields of photoelectric materials,chiral resolution,enantiomeric sensors and asymmetric polymerization.