早期康复联合低分子肝素治疗对颈髓损伤患者下肢深静脉血栓形成的预防效果

Therapeutic Effect of Early Rehabilitation Combined low Molecular Weight Heparinfor Deep Venous Thrombosis in Patients with Cervical Spinal Cord Injury

目的:探讨早期康复联合低分子肝素治疗对颈髓损伤患者下肢深静脉血栓形成的预防效果。方法:收集2014年5月至2015年12月收治的113例颈髓损伤患者的临床资料进行回顾性分析,其中58例患者接受了早期康复联合低分子肝素治疗(观察组)、55例患者接受了单纯低分子肝素治疗(对照组)。结果:观察组患者DVT发生率为1.72%,显著低于对照组的16.36%,差异具有统计学意义(P<0.05)。两组患者治疗后D-Dimer水平,血液流变性指标ηb、Fib、PAG、MST较治疗前的下降幅度均以观察组大于对照组,差异存在统计学意义(P<0.05)。结论:颈髓损伤患者早期给予积极、正确的康复治疗联合低分子肝素治疗,可以有效降低其DVT的发生。

Objective:To study the effect of early rehabilitation combined low molecular weight heparin(LMWH)for deep venous thrombosis(DVT)in patients with cervical spinal cord injury.Methods:The clinical data of 113 patients with cervical spinal cord injury admitted from May 2014 to December 2015 were retrospectively analyzed.Among them,58 patients received early rehabilitation combined with low molecular weight heparin therapy(observation group),and 55 patients received simple Low molecular weight heparin treatment(control group).Results:The incidence rate of DVT in the observation group was 1.72%,which was lower than that in the control group(16.36%)(P<0.05).The decreased levels between after treatment and before treatment of D-Dimer and the blood rheology indicators hb,Fib,PAG,MST were all greater in the observation group than in the control group(P<0.05).Conclusion:It can prevent the occurrence of deep venous thrombosis with proper early rehabilitation combined low molecular weight heparin for patients with cervical spinal cord injury.