改良Miccoli术式联合纳米碳示踪剂在甲状腺全切术中应用效果及安全性分析

Effect and Safety of Modified Miccoli Procedure combined with Carbon Nanotracer in Total Thyroidectomy

目的:探讨改良Miccoli术式联合纳米碳示踪剂在甲状腺全切术中应用效果及安全性。方法:选择2016年1月至2018年2月我院接诊的80例甲状腺癌症患者,通过随机数表法分为观察组和对照组,每组40例,对照组给改良Miccoli术式治疗,观察组在对照组基础上联合纳米碳示踪剂。比较两组术后指标、淋巴结的清除情况、淋巴结转移率、甲状旁腺误切率、甲状旁腺激素、血钙的变化和术后并发症。结果:两组手术时间、术中出血量、住院时间比较差异无统计学意义(P>0.05);观察组淋巴结清除数多于对照组(P<0.05);观察组甲状旁腺误切率低于对照组(P<0.05);两组甲状旁腺激素和血钙比较具有交互作用(P<0.05);观察组术后并发症低于对照组(P<0.05)。结论:改良后的Miccoli术式联合纳米碳示踪剂,能减轻对甲状腺的损伤,且安全有效。

Objective:To study curative efficacy of the improved Miccoli surgery combined with nano-carbon tracer in treatment of total thyroidectomy and its effects on safety analysis.Methods:80 patients of thyroid carcinoma who received therapy from January 2016 to February 2018 in our hospital were selected as research objects,according to the random number table,each group of 40 cases,the control group was treated with the improved Miccoli surgery,while the observation group was combined with nano-carbon tracer injection on the basis of the control group.postoperative indicators,lymph node dissection,lymph node metastasis rate,misresection rate of parathyroid gland,parathyroid hormone,changes of serum calcium and postoperative complications were compared between the two groups.Results:There was no significant difference in the operative time,intraoperative bleeding volume,length of stay between the two groups(P>0.05).The number of lymph node dissection in the observation group was more than the control group(P<0.05).The misresection rate of parathyroid gland in the observation group was lower than those in the control group(P<0.05).There was interaction between parathyroid hormone and blood calcium in the two groups.(P<0.05).The postoperative complications in the observation group was lower than those in the control group(P<0.05).Conclusion:The modified Miccoli procedure combined with nano-carbon tracer can alleviate thyroid injury and is safe and effective.