全身麻醉药物与术后认知功能障碍的研究进展

Research Progress of General Anesthesia Drugs and Postoperative Cognitive Impairment

术后认知功能障碍是一种多发于老年患者的中枢神经系统并发症,目前发病机制尚未明确,患者自身状况、麻醉方式、麻醉药物以手术方式等都可能会影响术后认知功能障碍的发生。随着医学研究的不断深入,对全身麻醉作用原理和认知功能障碍致病机制的研究辨明,发现全身麻醉药物可广泛地影响患者的认知功能,此方面研究能为临床医生合理选择麻醉药物提供一定的指导。

The post-operative cognitive dysfunction is a kind of central nervous system complication that is multiple in the elderly.At present,the pathogenesis is not clear,the patient's own condition,the way of anesthesia,the narcotic drug,the operation mode and so on can affect the occurrence of post-operative cognitive dysfunction.With the development of the medical research,the research and identification of the mechanism of general anesthesia and the pathogenesis of cognitive dysfunction,it has been recognized that the general anesthesia medicine has wide influence on the cognitive function of the patient,and the study can provide some guidance for the rational choice of the narcotic drugs by the clinical doctors.