粪菌移植的研究进展

Research progress of fecal microbiota transplantation

粪菌移植(fecal microbiota transplantation,FMT)是针对肠道疾病一种新兴的治疗措施,尤其针对复发性难辨梭状芽孢杆菌感染(clostridium difficile infection,CDI)疗效尤为突出,可重建患者肠道菌群,有效纠正肠道菌群紊乱.近年来粪菌移植的临床应用越来越广泛,本研究就粪菌移植的发展简史、操作流程、临床应用及不良反应等方面作一综述.

Fecal microbiota transplantation(FMT)is a new treatment method for intestinal diseases,especially for recurrent Clostridium difficile infection(CDI),which is very effective.It can reconstruct the intestinal flora of patients and effectively correct the disorder of intestinal flora.In recent years,the clinical application of fecal transplantation has been more and more extensive.This paper reviews the development history,operation process,clinical application and adverse reactions of fecal transplantation.