酶促还原过程中辅因子的再生研究

Regeneration of Cofactors in Enzymatic Reduction

辅因子在酶催化的合成反应中具有重要作用,其昂贵的价格使得辅因子的再生有了一定的意义.辅因子的再生方法包括化学法、电化学法、光化学法和酶法,文章着重介绍了烟酰胺类辅因子(NADH/NADPH)再生方法的发展状况和实际应用,从而突出酶法的应用优势.

Cofactors play an important role in enzyme-catalyzed synthesis reactions,and the regeneration of cofactors has certain significance because of its high cost.The regeneration methods of cofactors include chemical methods,electrochemical methods,photochemical methods,and enzymatic methods.This article focuses on the development status and practical applications of various regeneration methods for nicotinamide cofactors(NADH/NADPH),so as to highlight the obvious advantages of enzymatic method.