左氧氟沙星静脉滴注对预防经皮肾镜取石术后感染的应用效果分析

Effect of Levofloxacin Intravenous Drip on Prevention of Infection After Percutaneous Nephrolithotomy

目的分析左氧氟沙星静脉滴注对预防经皮肾镜取石术后感染的应用效果。方法选取2017年6月—2018年9月在南阳市第二人民医院行经皮肾镜取石术治疗的患者124例为研究对象,按照随机数表法将其分为两组,各62例。对照组术前1 h给予左氧氟沙星静脉滴注,观察组于术前3 d及术前1 h给予左氧氟沙星静脉滴注。观察两组手术时间、术后血红蛋白水平、肾盂内压力、结石清除率及感染发生率。结果两组手术时间、术后血红蛋白水平、肾盂内压力及结石清除率比较,差异无统计学意义(P>0.05);对照组术后发热、菌尿发生率高于观察组,差异有统计学意义(P<0.05)。结论左氧氟沙星静脉滴注治疗可有效预防经皮肾镜取石术术后感染发生,且术前早期应用预防效果更佳。

Objective To analyze the effect of levofloxacin intravenous drip on prevention of infection after percutaneous nephroli?thotomy.Methods 124 patients who underwent percutaneous nephrolithotomy in the hospital from June,2017 to September,2018 were divided into two groups according to random table method,with 62 cases in each group.The control group received levofloxacin intravenous drip 1 hour before operation,and the observation group received levofloxacin intravenous drip 3 days before operation and 1 hour before operation.The operation time,postoperative hemoglobin level,renal pelvis pressure,stone clearance rate and infec?tion rate were observed.Results There was no significant difference in the operation time,postoperative hemoglobinrenal pelvis pres?sure and stone clearance rate between two groups(P>0.05),but the incidence of postoperative fever and bacteriuria in the control group was higher than that in the observation group(P<0.05).Conclusion Intravenous infusion of levofloxacin can effectively prevent infection after percutaneous nephrolithotomy,and the early application of levofloxacin is more effective in preventing infection after percutaneous nephrolithotomy.