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血浆置换联合糖皮质激素治疗视神经脊髓炎谱系疾病合并抗磷脂综合征一例 被引量:4

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摘要 1例39岁女性患者因双眼反复视力下降8.5年就诊眼科,病程中出现顽固性呃逆、呕吐、上半身持续瘙痒感等症状,血清水通道蛋白4抗体阳性,诊断视神经脊髓炎谱系疾病合并抗磷脂综合征,入院后给予血浆置换联合糖皮质激素冲击治疗,加用免疫抑制剂预防复发,随访16个月病情稳定。
出处 《中华眼科杂志》 CAS CSCD 北大核心 2019年第11期866-868,共3页 Chinese Journal of Ophthalmology
基金 国家高技术研究发展计划(863计划)(2015AA020511)。
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  • 1张晓君,王薇,王虔,魏文斌,魏永祥.视神经炎病因学临床分析[J].中华眼底病杂志,2006,22(6):367-369. 被引量:58
  • 2Li R, Daguzan M, Vandermijnsbrugge F, et al. Both IgG and IgM anti-beta2 glycoprotein I antibodies as- says are clinically useful to the antiphospholipid syn- drome diagnosis [J]. Acta Clin Belg, 2014, 25 (2) : 246- 250.
  • 3Chighizola CB, Gerosa M, Meroni PL, et al. New tests to detect antiphospholipid antibodies., anti-domain I beta2 gtycoprotein I antibodies[J]. Curr Rheumatol Rep,2014,16(2) :402.
  • 4Rahgozar S. Revisiting beta 2 glycopmtein I, the major autoantigen in the antiphospholipid syndrome[J]. I- ran J Immunol,2012,9(2) :73-85.
  • 5Agar C,van Os GM, Morgelin M, et al. Beta 2 glyco- protein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syn- drome[J]. Blood,2010,116(8) :1336-1343.
  • 6de Laat B, van Berkel M, Urbanus RT, et al. Immune responses against domain I of beta 2 glycoprotein I are driven by conformational changes : domain I of be- ta 2 glycoprotein I harbors a cryptic immunogenie epitope[J]. Arth Rheum,2011,63(12) :3960-3968.
  • 7Gharavi AE, Pierangeli SS, Espinola RG, et al. An- tiphospholipid antibodies induced in mice by immunb. zation with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo [J]. Arth Rheum,2002,46(2) :545-552.
  • 8van Os GM, Meijers JC, Agar C, et al. Induction of anti Beta 2 glycoprotein I autoantibodies in mice by protein H of Streptococcus pyogenes [J]. J Thromb Haemost, 2011,9 (12) : 2447-2456.
  • 9Agar C,de Groot PG,Morgelin M,et al. β2 glycopro- tein I: a novel component of innate immunity[J]. Blood,2011,117(25) :6939-6947.
  • 10Fischetti F, Durigutto P, Pellis V, et al. Thrombus formation induced by antibodies to beta 2 glycopro tein I is complement dependent and requires a prim ing factor[J]. Blood, 2005,106 (7) : 2340-2346.

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