衣原体疫苗研究进展

Progress of development of chlamydial vaccine

衣原体是一类具备双相发育周期、专性细胞内寄生的原核细胞型微生物,其在世界各个国家普遍存在,同时可以在广泛的宿主范围内引起疾病,主要引起生殖道、眼部、呼吸道和心血管系统等疾病,对全球造成持续的负担,带来相当大的公共卫生挑战。疫苗接种被认为是预防衣原体感染的最佳方法,因此急需研发有效的疫苗来预防和控制衣原体的感染。近年来有较多学者就衣原体疫苗进行研究并取得了一定的进展,本文就衣原体疫苗的最新研究进展作一简要介绍。

Chlamydiae are a phylum of obligate intracellular bacteria with a unique biphasic development cycle.Chlamydiae are prevalent in various countries and can cause many diseases in a wide range of hosts,including genitalia,ocular,respiratory tract and cardiovascular system diseases,which result in a sustained global burden,and poses considerable public health challenges.Vaccination has been considered to be the best way to prevent chlamydial infection,so it is urgent to develop an effective vaccine.In recent years,many scholars have been conducting research on chlamydial vaccine and also have made some progress.This review aims to give a brief introduction to the latest research progress of chlamydial vaccine.