血液学炎症标志物在鼻咽癌中的临床应用价值

Clinical practice value of hematological inflammation biomarkers in nasopharyngeal carcinoma

炎症可促进肿瘤的发生、发展、浸润、转移。鼻咽癌中血液学炎症标志物异常(外周血中性粒细胞淋巴细胞比值、血小板淋巴细胞比值、全身免疫炎症指数、C反应蛋白等)是炎症在肿瘤发展中的临床表现,通过对鼻咽癌患者中的血液学炎症标志物检测可获得提示预后的信息,对现有的预后指标起到补充作用,有助于指导个体化临床治疗策略的制定,为临床实践提供更多的思路。

Inflammation promotes tumor initiate,progress,invade and metastasize.Hematological inflammation biomarkers in nasopharyngeal carcinoma(peripheral blood neurtrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,systemic immune-inflammation index and C-creative protein)are the expressions of inflammation in the progress of nasopharyngeal carcinoma.The information of prognosis can be obtained by testing the hematological inflammation biomarkers in nasopharyngeal carcinoma patients.These biomarkers are the supplement for the current prognosis predictive indices and they can be used to guide the clinical practice,which will provide more ideas.