上海市郊区某镇60岁以上老人脂肪肝患病现状及其危险因素

Prevalence and risk factors of fatty liver in elderly people aged 60 and over in a town of Shanghai suburb

目的了解上海市郊区某镇>60岁老人脂肪肝患病现状及其危险因素,为制定更好的社区脂肪肝防治策略提供科学依据。方法选择2018年4-12月在上海市郊区某镇社区卫生服务中心参与>60岁居民健康检查的12 135名老人,收集其健康检查资料和个人信息,分析脂肪肝的患病情况,应用单因素分析和多因素logistic回归分析探讨其危险因素。结果参与健康检查且资料完整的>60岁老人共12 135人,经B超诊断为脂肪肝患者的共4 794例,患病率为39.51%,男性患病率低于女性(χ^2=17.850,P<0.01),脂肪肝患病率随年龄增长而降低(χ^2=143.675,P<0.01),城镇地区脂肪肝患病率高于农村(χ^2=247.307,P<0.01),吸烟者脂肪肝患病率低于不吸烟者(χ^2=39.232,P<0.01),坚持运动者脂肪肝患病率低于不坚持运动者(χ^2=4.034,P<0.05),超重与肥胖、有高血压、高血脂和高血糖者的脂肪肝患病率均高于无相应因素者,且差异均有统计学意义(均P<0.05)。多因素logistic模型分析结果显示,<70岁、城镇地区、不坚持运动、超重与肥胖、高血压、高血脂以及高血糖者脂肪肝患病危险性高。结论上海市郊区某镇>60岁老人脂肪肝患病较为严重,且脂肪肝患病的危险因素较多,需要根据研究结果针对不同人群开展生活方式干预和健康教育工作,以降低脂肪肝患病率。

Objective To understand the prevalence of fatty liver and its risk factors among the elderly over 60 years old in a suburban town of Shanghai, provide scientific basis for formulating better strategies for prevention and treatment of fatty liver in community. Methods 12 135 elderly people over 60 years old, who participated in the physical examination in a community health service center of a town in Shanghai suburb from April 2018 to December 2018, were selected. Their physical examination data and personal information were collected to analyze the prevalence of fatty liver. The risk factors were analyzed by univariate analysis and multivariate logistic regression analysis. Results A total of 12 135 persons over 60 years old participated in physical examination with complete data, there were 4 794 cases of fatty liver diagnosed by B-mode ultrasonography, and the prevalence of fatty liver was 39.51%. The prevalence of fatty liver in males was lower than that in females (χ^2=17.850, P<0.01). The prevalence of fatty liver decreased with age (χ^2=143.675, P<0.01). The prevalence of fatty liver in urban areas was higher than that in rural areas(χ^2=247.307, P<0.01), the prevalence of fatty liver in smokers was higher than that in non-smokers(χ^2=39.232,P<0.01), while the prevalence of fatty liver in exercise-persistent people was lower than that in non-exercise-persistent people(χ^2=4.034, P <0.05). The prevalence of fatty liver in overweight and obese people, those with hypertension, hyperlipidemia and hyperglycemia were higher than those without corresponding factors, and the difference was statistically significant(all P<0.05).Multivariate Logistic model analysis showed that under 70 years old, urban areas, non-exercise, overweight and obesity,hypertension, hyperlipidemia and hyperglycemia were at high risk of fatty liver disease. Conclusion Fatty liver is a serious disease among the elderly over 60 years old in a suburban town of Shanghai, and there are many factors related to fatty liver. It is necessary to carry out lifestyle intervention and health education for different people according to the results of the study in order to reduce the prevalence of fatty liver.